Wrapper around multiple PipeOps to help in creation of complex survival to reduction methods. Three reductions are currently implemented, see details.

## Usage

```
pipeline_survtoregr(
method = 1,
regr_learner = lrn("regr.featureless"),
distrcompose = TRUE,
distr_estimator = lrn("surv.kaplan"),
regr_se_learner = NULL,
surv_learner = lrn("surv.coxph"),
survregr_params = list(method = "ipcw", estimator = "kaplan", alpha = 1),
distrcompose_params = list(form = "aft"),
probregr_params = list(dist = "Uniform"),
learnercv_params = list(resampling.method = "insample"),
graph_learner = FALSE
)
```

## Arguments

- method
`integer(1)`

Reduction method to use, corresponds to those in`details`

. Default is`1`

.- regr_learner
LearnerRegr

Regression learner to fit to the transformed TaskRegr. If`regr_se_learner`

is`NULL`

in method`2`

, then`regr_learner`

must have`se`

predict_type.- distrcompose
`logical(1)`

For methods`1`

and`3`

if`TRUE`

(default) then PipeOpDistrCompositor is utilised to transform the deterministic predictions to a survival distribution.- distr_estimator
LearnerSurv

For methods`1`

and`3`

if`distrcompose = TRUE`

then specifies the learner to estimate the baseline hazard, must have predict_type`distr`

.- regr_se_learner
LearnerRegr

For method`2`

if`regr_learner`

is not used to predict the`se`

then a`LearnerRegr`

with`se`

predict_type must be provided.- surv_learner
LearnerSurv

For method`3`

, a LearnerSurv with`lp`

predict type to estimate linear predictors.- survregr_params
`list()`

Parameters passed to PipeOpTaskSurvRegr, default are survival to regression transformation via`ipcw`

, with weighting determined by Kaplan-Meier and no additional penalty for censoring.- distrcompose_params
`list()`

Parameters passed to PipeOpDistrCompositor, default is accelerated failure time model form.- probregr_params
`list()`

Parameters passed to PipeOpProbregr, default is Uniform distribution for composition.- learnercv_params
`list()`

Parameters passed to PipeOpLearnerCV, default is to use insampling.- graph_learner
`logical(1)`

If`TRUE`

returns wraps the Graph as a GraphLearner otherwise (default) returns as a`Graph`

.

## Details

Three reduction strategies are implemented, these are:

Survival to Deterministic Regression A

PipeOpTaskSurvRegr Converts TaskSurv to TaskRegr.

A LearnerRegr is fit and predicted on the new

`TaskRegr`

.PipeOpPredRegrSurv transforms the resulting PredictionRegr to PredictionSurv.

Optionally: PipeOpDistrCompositor is used to compose a

`distr`

predict_type from the predicted`response`

predict_type.

Survival to Probabilistic Regression

PipeOpTaskSurvRegr Converts TaskSurv to TaskRegr.

A LearnerRegr is fit on the new

`TaskRegr`

to predict`response`

, optionally a second`LearnerRegr`

can be fit to predict`se`

.PipeOpProbregr composes a

`distr`

prediction from the learner(s).PipeOpPredRegrSurv transforms the resulting PredictionRegr to PredictionSurv.

Survival to Deterministic Regression B

PipeOpLearnerCV cross-validates and makes predictions from a linear LearnerSurv with

`lp`

predict type on the original TaskSurv.PipeOpTaskSurvRegr transforms the

`lp`

predictions into the target of a TaskRegr with the same features as the original TaskSurv.A LearnerRegr is fit and predicted on the new

`TaskRegr`

.PipeOpPredRegrSurv transforms the resulting PredictionRegr to PredictionSurv.

Optionally: PipeOpDistrCompositor is used to compose a

`distr`

predict_type from the predicted`lp`

predict_type.

Interpretation:

Once a dataset has censoring removed (by a given method) then a regression learner can predict the survival time as the

`response`

.This is a very similar reduction to the first method with the main difference being the distribution composition. In the first case this is composed in a survival framework by assuming a linear model form and baseline hazard estimator, in the second case the composition is in a regression framework. The latter case could result in problematic negative predictions and should therefore be interpreted with caution, however a wider choice of distributions makes it a more flexible composition.

This is a rarer use-case that bypasses censoring not be removing it but instead by first predicting the linear predictor from a survival model and fitting a regression model on these predictions. The resulting regression predictions can then be viewed as the linear predictors of the new data, which can ultimately be composed to a distribution.

## Examples

```
if (FALSE) { # \dontrun{
if (requireNamespace("mlr3pipelines", quietly = TRUE)) {
library("mlr3")
library("mlr3pipelines")
task = tsk("rats")
# method 1 with censoring deletion, compose to distribution
pipe = ppl(
"survtoregr",
method = 1,
regr_learner = lrn("regr.featureless"),
distrcompose = TRUE,
survregr_params = list(method = "delete")
)
pipe$train(task)
pipe$predict(task)
# method 2 with censoring imputation (mrl), one regr learner
pipe = ppl(
"survtoregr",
method = 2,
regr_learner = lrn("regr.featureless", predict_type = "se"),
survregr_params = list(method = "mrl")
)
pipe$train(task)
pipe$predict(task)
# method 3 with censoring omission and no composition, insample resampling
pipe = ppl(
"survtoregr",
method = 3,
regr_learner = lrn("regr.featureless"),
distrcompose = FALSE,
surv_learner = lrn("surv.coxph"),
survregr_params = list(method = "omission")
)
pipe$train(task)
pipe$predict(task)
}
} # }
```